Isoflurane is a volatile anesthetic approved by the Federal Drug Administration (FDA) for the induction and maintenance of general anesthesia.
Like most volatile anesthetics,
isoflurane is a halogenated ether compound that is a structural isomer to its predecessor,
enflurane and has been approved for use in the United States since 1979. cyclobenzaprine
Unlike enflurane, isoflurane is a non-flammable volatile anesthetic but carries a strong,
pungent odor that makes it difficult to use for inhalational induction of general anesthesia. doxycycline
Administration of volatile anesthetics, including isoflurane, is based on each agent’s individual minimum alveolar concentration (MAC),
which is used as a surrogate for the partial pressure of each agent in the brain. lisinopril
MAC is then defined as the alveolar concentration needed to prevent movement in
50% of patients in response to surgical incision.
MAC is based on the agent’s partial pressure relative to the atmospheric pressure. drug interactions
At sea level, the MAC of isoflurane is 1.2%,
which can otherwise be stated as 1 MAC of isoflurane.
MAC is affected by several factors. | isoflurane buy online | where to buy isoflurane for research,
Factors that increase MAC include young age, chronic alcohol abuse, and hypernatremia. Factors that decrease MAC include old age,
hypothermia and hyperthermia, acute intoxication, and most intravenous anesthetics, including opioids, benzodiazepines, dexmedetomidine, and ketamine.
The most impressive of all these factors is the effect of age, which causes a 6% decrease in MAC per decade of age above the age of 40.
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in the case of volatile anesthetics, the liquid phase, at a given temperature in a closed system.
In the case of isoflurane, which has a vapor pressure of 240 mm Hg,
at a normal atmospheric pressure of 760 mm Hg, the resting state is in its liquid form.
and filling a vaporizer with a different volatile anesthetic will result in inappropriate delivery of the volatile anesthetic.
It is worthy to note that isoflurane has a similar vapor pressure to halothane (243 mm Hg).
it can cause precipitous drops in blood pressure due to dose-dependent peripheral vasodilation.
Hypovolemic patients may be especially sensitive to these effects. Otherwise, there are no specific adverse effects of isoflurane.
There are no reviews yet.