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Isoflurane is a volatile anesthetic approved by the Federal Drug Administration (FDA) for the induction and maintenance of general anesthesia.
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Unlike enflurane, isoflurane is a non-flammable volatile anesthetic but carries a strong,
pungent odor that makes it difficult to use for inhalational induction of general anesthesia. doxycycline
Administration of isoflurane anesthesia
Administration of volatile anesthetics, including isoflurane, is based on each agent’s individual minimum alveolar concentration (MAC),
50% of patients in response to surgical incision.
MAC is based on the agent’s partial pressure relative to the atmospheric pressure. drug interactions
At sea level, the MAC of isoflurane is 1.2%,
MAC is affected by several factors.
Factors that increase MAC include young age, chronic alcohol abuse, and hypernatremia. Factors that decrease MAC include old age,
hypothermia and hyperthermia, acute intoxication, and most intravenous anesthetics, including opioids, benzodiazepines, dexmedetomidine, and ketamine.
The most impressive of all these factors is the effect of age, which causes a 6% decrease in MAC per decade of age above the age of 40.
in the case of volatile anesthetics, the liquid phase, at a given temperature in a closed system.
In the case of isoflurane, which has a vapor pressure of 240 mm Hg,
at a normal atmospheric pressure of 760 mm Hg, the resting state is in its liquid form.
and filling a vaporizer with a different volatile anesthetic will result in inappropriate delivery of the volatile anesthetic.
It is worthy to note that isoflurane has a similar vapor pressure to halothane (243 mm Hg).
Adverse Effects of Isoflurane buy online
it can cause precipitous drops in blood pressure due to dose-dependent peripheral vasodilation.
Hypovolemic patients may be especially sensitive to these effects. Otherwise, there are no specific adverse effects of isoflurane.
It is worthy to note that isoflurane has a similar vapor pressure to halothane (243 mm Hg).
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